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五年前，赵南天和濮芊芊设计坑杀了男主曹行的哥哥曹谦，并且将所有的罪名都诬陷到了曹行的身上。曹行含冤入狱，偶然得到了一本失传的失传的医武古籍...五年后出狱归来，面对家族落败，母亲妹妹受尽欺凌，曹行奋起抵抗。。巧娘和麻瘋病的父親相依為命，某夜巧娘私藏麻瘋病父親之事敗露，巧娘在目睹父親被活活燒死後被放在掛著疫旗的小船飄向遠方，恰逢台灣島陳福生大船路過救下了巧娘，甦醒後巧娘出逃被人販子賣至親生母親做老鴇的妓院，之後巧娘輾轉成為陳家丫鬟，陳家女主人病逝前托孤給巧娘，巧娘也成為陳家的繼室，與陳福生又生一子。巧娘雖善良盡職，仍被陳家親威排斥。陳福生死，巧娘更被趕走，帶著親生子文華回娘家居住。文華成長，為身世憤恨出外流浪，到蘇州以賣鴨蛋為生，又娶當地財主之女致富，惟仍不認生母，巧娘孤然一生以終。Grace becomes addicted to opioids after suffering a sports injury. She's ready to leave her addiction behind under her mother's watch, but her past won't let her go: Richie kidnaps her in a motel room to sell her into human trafficking.。